Description

2-[2-(3-Piperidinyl)Ethoxy]-5-(Trifluoromethyl)-Pyridine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 1219967-33-5. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within the central nervous system (CNS) and other specialized drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold in structure-activity relationship (SAR) studies and lead optimization processes.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component in the manufacture of investigational and commercial APIs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug discovery and development projects.
• Biochemical Research: Employed in the study of biological targets and mechanisms where its specific molecular architecture is relevant.
• Process Chemistry & Scale-Up: Utilized in the development and optimization of robust, scalable synthetic routes for pharmaceutical production.

Basic Information

Item	Detail
Product Name	2-[2-(3-Piperidinyl)Ethoxy]-5-(Trifluoromethyl)-Pyridine Hydrochloride
CAS No.	1219967-33-5
Molecular Formula	C13H17F3N2O•HCl
Molecular Weight	310.75 g/mol
Synonyms	5-(Trifluoromethyl)-2-[2-(3-piperidinyl)ethoxy]pyridine hydrochloride; 2-[2-(3-Piperidyl)ethoxy]-5-(trifluoromethyl)pyridine HCl; 3-[2-[5-(Trifluoromethyl)-2-pyridyl]oxyethyl]piperidine hydrochloride; 1219967-33-5; 2-(2-(Piperidin-3-yl)ethoxy)-5-(trifluoromethyl)pyridine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-[2-(3-Piperidinyl)Ethoxy]-5-(Trifluoromethyl)-Pyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP starting material applications. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.