Description

2-[(Tetrahydro-2H-Pyran-4-Ylmethyl)Amino]-Isonicotinic Acid is a high-value pharmaceutical intermediate and organic building block. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals, offering a versatile pyridine core with a protected amino functionality. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry research.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the development and scale-up of APIs for various therapeutic areas.
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides.
• Ligand and Catalyst Development: Utilized in organometallic chemistry for creating novel ligands and catalytic systems.
• Chemical Biology Probes: Acts as a scaffold for developing molecular probes to study biological systems.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	2-[(Tetrahydro-2H-Pyran-4-Ylmethyl)Amino]-Isonicotinic Acid
CAS No.	1219960-34-5
Molecular Formula	C12H16N2O3
Molecular Weight	236.27 g/mol
Synonyms	2-[(Tetrahydro-2H-pyran-4-ylmethyl)amino]isonicotinic acid; 2-[(Tetrahydropyran-4-ylmethyl)amino]pyridine-4-carboxylic acid; 4-Pyridinecarboxylic acid, 2-[(tetrahydro-2H-pyran-4-ylmethyl)amino]-; 2-[(Oxan-4-ylmethyl)amino]pyridine-4-carboxylic acid; Isonicotinic acid, 2-[(tetrahydro-2H-pyran-4-ylmethyl)amino]-; THPMA-Isonicotinic Acid
EINECS	Contact for details

Quality Control

Our 2-[(Tetrahydro-2H-Pyran-4-Ylmethyl)Amino]-Isonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.