Description

2-Bromo-6-(4-Piperidinylmethoxy)Pyridinehydrochloride is a high-purity, advanced pharmaceutical intermediate. This compound matters as a critical building block in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other targeted therapies. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of small molecule kinase inhibitors.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Biochemical Tool Compound: Potential use in the development of biochemical probes for target validation in biological pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and methodology development.

Basic Information

Product Name	2-Bromo-6-(4-Piperidinylmethoxy)Pyridinehydrochloride
CAS No.	1219957-03-5
Molecular Formula	C11H16BrN2O·HCl
Molecular Weight	307.63 g/mol (Free base: 271.17 g/mol)
Synonyms	2-Bromo-6-[(piperidin-4-yl)methoxy]pyridine hydrochloride; 4-[(6-Bromopyridin-2-yl)oxymethyl]piperidine hydrochloride; 6-Bromo-2-((4-piperidinyl)methoxy)pyridine HCl; 2-Bromo-6-(piperidin-4-ylmethoxy)pyridine HCl; 2-Bromo-6-(4-piperidylmethoxy)pyridine hydrochloride; 1219957-03-5; 2-Bromo-6-(4-piperidinylmethoxy)pyridine HCl salt
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-(4-Piperidinylmethoxy)Pyridinehydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all relevant specifications. We support cGMP compliance for advanced intermediates intended for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.