Description

(R)-(3-tert-Butoxycarbonylamino-Piperidin-2-Yl)-Acetic Acid Ethyl Ester is a high-purity chiral piperidine derivative, serving as a critical building block in modern pharmaceutical synthesis. This compound is valued for its role in constructing complex molecules with defined stereochemistry, which is essential for developing active pharmaceutical ingredients (APIs) with high efficacy and specificity. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Peptidomimetic Chemistry: Used to introduce constrained piperidine scaffolds into peptide analogs to enhance metabolic stability and bioavailability.
• Asymmetric Synthesis: Employed as a starting material or intermediate in catalytic asymmetric reactions to construct enantiomerically pure compounds.
• Medicinal Chemistry Research: Serves as a versatile building block for constructing focused libraries in structure-activity relationship (SAR) studies.
• API Development: Integral in the synthetic route for advanced pharmaceutical intermediates leading to final active ingredients.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for pharmaceutical clients.

Basic Information

Product Name	(R)-(3-tert-Butoxycarbonylamino-Piperidin-2-Yl)-Acetic Acid Ethyl Ester
CAS No.	1219132-56-5
Molecular Formula	C15H28N2O4
Molecular Weight	300.40 g/mol
Synonyms	Ethyl (R)-2-(3-((tert-Butoxycarbonyl)amino)piperidin-2-yl)acetate; (R)-2-(3-(Boc-amino)piperidin-2-yl)acetic acid ethyl ester; tert-Butyl N-[(3R)-2-(2-ethoxy-2-oxoethyl)piperidin-3-yl]carbamate; Boc-3-amino-(R)-2-piperidineacetic acid ethyl ester; (R)-Ethyl 2-(3-(Boc-amino)piperidin-2-yl)acetate; (2R)-2-[3-[(2-Methylpropan-2-yl)oxycarbonylamino]piperidin-2-yl]acetic acid ethyl ester; Boc-D-3-Amino-2-piperidineacetic acid ethyl ester
EINECS	Contact for details

Quality Control

Our (R)-(3-tert-Butoxycarbonylamino-Piperidin-2-Yl)-Acetic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-grade pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.