Description

tert-Butyl n-(2-Methylpyridin-4-Yl)Carbamate is a high-purity, advanced pharmaceutical intermediate primarily used in the synthesis of complex active pharmaceutical ingredients (APIs). This compound is valued for its role as a key building block in medicinal chemistry, particularly for introducing the protected carbamate functional group. It is essential for research and development laboratories and production facilities in the pharmaceutical and agrochemical sectors seeking reliable, high-quality intermediates for scale-up and process optimization.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its pyridine-based structure.
• Organic Synthesis: Serves as a versatile reagent for introducing tert-butoxycarbonyl (Boc) protected amine groups in complex multi-step syntheses.
• Chemical Reference Standard: Employed as a high-purity standard in analytical laboratories for method development and quality control.
• Academic & Contract Research: Utilized in university and CRO settings for medicinal chemistry programs and process chemistry studies.

Basic Information

Product Name	tert-Butyl n-(2-Methylpyridin-4-Yl)Carbamate
CAS No.	1219112-94-3
Molecular Formula	C12H18N2O2
Molecular Weight	222.29 g/mol
Synonyms	4-[(tert-Butoxycarbonyl)amino]-2-methylpyridine; 2-Methyl-4-aminopyridine N-Boc derivative; tert-Butyl (2-methylpyridin-4-yl)carbamate; Boc-2-Methyl-4-aminopyridine; N-Boc-2-methyl-4-aminopyridine; 4-(Boc-amino)-2-methylpyridine; 2-Methyl-4-(Boc-amino)pyridine; 1219112-94-3
EINECS	Contact for details

Quality Control

Our tert-Butyl n-(2-Methylpyridin-4-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles for pharmaceutical intermediates to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and moisture. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.