Description

2-Bromo-1,8-Naphthyridin-3-Amine is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. This compound matters for its crucial role as a precursor in the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research and other therapeutic areas. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive naphthyridine core.
• Material Science: Serves as a precursor for creating functional organic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Chemical Biology: Employed as a molecular probe or tag in biochemical assays and proteomics research.
• Academic & Contract Research: Essential for methodological development in organic chemistry and for synthesizing novel compound libraries.

Basic Information

Product Name	2-Bromo-1,8-Naphthyridin-3-Amine
CAS No.	1219026-93-3
Molecular Formula	C8H6BrN3
Molecular Weight	224.06 g/mol
Synonyms	3-Amino-2-bromo-1,8-naphthyridine; 2-Bromo-1,8-naphthyridin-3-amine; 1,8-Naphthyridine, 3-amino-2-bromo-; 2-Bromo-3-amino-1,8-naphthyridine; 1219026-93-3; 2-Br-1,8-Nap-3-NH2
EINECS	Contact for details

Quality Control

Our 2-Bromo-1,8-Naphthyridin-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.