Description

Methyl 2,2-Dimethyl-3-(Tetrahydro-2H-Pyran-2-Yloxy)Propanoate is a high-purity, protected ester intermediate of significant value in advanced organic synthesis. This compound matters because it provides a versatile and reactive building block for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists for applications in medicinal chemistry, including the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key protected synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile building block for constructing novel molecular scaffolds in drug discovery programs.
• Agrochemical Synthesis: Used in the development and production of advanced pesticides, herbicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring precise stereochemistry.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and catalysis studies.
• Peptide Mimetics & Prodrug Synthesis: Useful for introducing ester-protected side chains or creating prodrug formulations.

Basic Information

Product Name	Methyl 2,2-Dimethyl-3-(Tetrahydro-2H-Pyran-2-Yloxy)Propanoate
CAS No.	1218915-52-6
Molecular Formula	C11H20O4
Molecular Weight	216.27 g/mol
Synonyms	Methyl 3-((Tetrahydro-2H-pyran-2-yl)oxy)-2,2-dimethylpropanoate; 2,2-Dimethyl-3-(tetrahydro-2H-pyran-2-yloxy)propanoic Acid Methyl Ester; THP-protected Methyl Dimethylmalonate Derivative; Methyl 2,2-dimethyl-3-((tetrahydro-2H-pyran-2-yl)oxy)propanoate; Propanoic acid, 2,2-dimethyl-3-((tetrahydro-2H-pyran-2-yl)oxy)-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2,2-Dimethyl-3-(Tetrahydro-2H-Pyran-2-Yloxy)Propanoate is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are kept tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.