Description

Pyrrolidin-1-Yl(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Yl)Methanone is a high-value boronic ester derivative, specifically designed as a key synthetic intermediate for advanced organic transformations. Its core value lies in enabling efficient cross-coupling reactions, which are fundamental for constructing complex molecular architectures in modern chemistry. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries, where it serves as a critical building block for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for small molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic ester reagent for forming carbon-carbon bonds, a cornerstone reaction in medicinal and process chemistry.
• Agrochemical Research: Used in the development of novel pesticides, herbicides, and fungicides requiring specific pyridine-based structures.
• Material Science & OLED Development: Acts as a precursor for creating organic electronic materials, including ligands for catalysts and components for light-emitting diodes.
• Chemical Biology & Probe Synthesis: Employed in the creation of molecular probes and labeled compounds for biochemical and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Pyrrolidin-1-Yl(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Yl)Methanone
CAS No.	1218790-21-6
Molecular Formula	C16H23BN2O3
Molecular Weight	302.18 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(1-pyrrolidinylcarbonyl)pyridine; (5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)(pyrrolidin-1-yl)methanone; 1-[5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carbonyl]pyrrolidine; 3-Pyrrolidine-1-carbonyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridine; Boronic acid, B-[5-(1-pyrrolidinylcarbonyl)-3-pyridinyl]-, 1,3,2-dioxaborolane ester
EINECS	Contact for details

Quality Control

Our Pyrrolidin-1-Yl(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Yl)Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.