Description

1-[(4-Chloro-2-Pyridinyl)Carbonyl]-2-Piperidinecarboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other specialized therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new chemical entities with improved efficacy and safety profiles.
• Process Chemistry Development: Serves as a critical starting material or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions for clinical trial material production.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and proprietary APIs.
• Academic & Institutional Research: Utilized in university and government laboratories for fundamental research in organic synthesis and bioorganic chemistry.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in analytical laboratories.

Basic Information

Product Name	1-[(4-Chloro-2-Pyridinyl)Carbonyl]-2-Piperidinecarboxylic Acid
CAS No.	1218724-36-7
Molecular Formula	C12H13ClN2O3
Molecular Weight	268.70 g/mol
Synonyms	2-Piperidinecarboxylic acid, 1-[(4-chloro-2-pyridinyl)carbonyl]-; 1-(4-Chloro-2-pyridinecarbonyl)pipecolic acid; 1-[(4-Chloro-2-pyridoyl)]-2-piperidinecarboxylic acid; 4-Chloro-2-pyridinecarboxylic acid pipecolic acid amide; (4-Chloro-pyridine-2-carbonyl)-piperidine-2-carboxylic acid; 1-(4-Chloro-2-pyridinecarbonyl)-2-piperidinecarboxylic acid; 1-(4-Chloro-2-pyridinylcarbonyl)-2-piperidinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 1-[(4-Chloro-2-Pyridinyl)Carbonyl]-2-Piperidinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production requirements. We support development with custom purity grades and specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.