Description

Rs-Cyclohexylglycine 1,1-Dimethylethyl Ester is a high-purity, non-natural amino acid derivative, specifically a protected glycine analog with a cyclohexyl substituent. This compound is a critical chiral building block in the synthesis of complex pharmaceutical intermediates and bioactive peptides. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of peptide-based drugs and protease inhibitors.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides with specific chiral activity.
• Peptide Chemistry: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis (SPPS).
• Organic Synthesis Building Block: Employed in asymmetric synthesis and medicinal chemistry for constructing complex molecular architectures.
• Bioconjugation & Linker Chemistry: Potential use in creating drug-linker systems for antibody-drug conjugates (ADCs) and other bioconjugates.
• Material Science Research: Investigated for incorporation into specialty polymers and foldamers with unique structural properties.

Basic Information

Product Name	Rs-Cyclohexylglycine 1,1-Dimethylethyl Ester
CAS No.	1218397-71-7
Molecular Formula	C₁₃H₂₅NO₂
Molecular Weight	227.34 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-D-cyclohexylglycine; Boc-D-Cyclohexylglycine; (R)-2-((tert-Butoxycarbonyl)amino)-2-cyclohexylacetic acid; tert-Butyl (R)-2-amino-2-cyclohexylacetate; D-Cyclohexylglycine tert-butyl ester; Boc-Cyh-OH; (R)-2-(Boc-amino)-2-cyclohexylacetic acid; N-Boc-D-cyclohexylglycine
EINECS	Contact for details

Quality Control

Our Rs-Cyclohexylglycine 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (HPLC), identity confirmation (IR, NMR), and impurity profiling to ensure it meets the high standards required for pharmaceutical R&D and cGMP applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.