Description

(S)-α-Methylaspartic Acid-4-tert-Butyl Ester, 98% Ee is a high-purity, chiral non-proteinogenic amino acid derivative, serving as a critical building block in advanced organic synthesis. Its defined stereochemistry and protected carboxyl group make it an invaluable intermediate for constructing complex molecules with precise spatial orientation. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients, peptide mimetics, and chiral catalysts.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of protease inhibitors, neuromodulators, and other active pharmaceutical ingredients (APIs).
• Peptidomimetics Research: Used to introduce constrained, non-natural amino acid residues into peptide backbones to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Building block for creating chiral herbicides, fungicides, and plant growth regulators with improved efficacy and environmental profile.
• Asymmetric Catalysis: Employed as a precursor for chiral ligands and organocatalysts used in stereoselective transformations.
• Biochemical Tool Development: Utilized in the design of enzyme inhibitors and probes for studying biological mechanisms and signal transduction pathways.
• Material Science: Potential monomer for synthesizing specialized polymers with unique chiral or functional properties.

Basic Information

Product Name	(S)-α-Methylaspartic Acid-4-tert-Butyl Ester, 98% Ee
CAS No.	1217977-71-3
Molecular Formula	C9H17NO4
Molecular Weight	203.24 g/mol
Synonyms	(S)-2-Amino-2-methylsuccinic acid 4-tert-butyl ester; (S)-2-Methylaspartic acid 4-tert-butyl ester; (S)-4-(tert-Butoxy)-2-methyl-2-aminosuccinic acid; tert-Butyl (S)-2-amino-2-methylsuccinate; (S)-α-Methylaspartic acid β-tert-butyl ester; (2S)-2-Amino-2-methylbutanedioic acid 4-tert-butyl ester
EINECS	Contact for details

Quality Control

Every batch of (S)-α-Methylaspartic Acid-4-tert-Butyl Ester is produced and tested under a strict quality management system. We guarantee a minimum enantiomeric excess (ee) of 98% and high chemical purity, verified by advanced chiral and analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with each shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.