Description

(R)-3-(Pyridin-2-Ylsulfanyl)-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals where stereochemical integrity is paramount. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel therapeutic agents, including potential enzyme inhibitors and receptor modulators.
• Asymmetric Synthesis: Serves as a versatile precursor for constructing complex, stereodefined molecular architectures in medicinal chemistry.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis and organometallic chemistry applications.
• Agrochemical Research: Employed as a building block in the synthesis of advanced crop protection agents and pesticides.
• Chemical Biology Probes: Useful for the development of molecular probes to study biological pathways and protein interactions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects.

Basic Information

Product Name	(R)-3-(Pyridin-2-Ylsulfanyl)-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1217850-83-3
Molecular Formula	C14H20N2O2S
Molecular Weight	280.39 g/mol
Synonyms	(R)-1-Boc-3-(pyridin-2-ylthio)pyrrolidine; (R)-tert-Butyl 3-(pyridin-2-ylthio)pyrrolidine-1-carboxylate; (R)-N-Boc-3-(2-pyridylthio)pyrrolidine; (R)-3-(2-Pyridylthio)-1-(tert-butoxycarbonyl)pyrrolidine; (R)-3-(Pyridin-2-ylsulfanyl)pyrrolidine-1-carboxylic acid tert-butyl ester; 1-Pyrrolidinecarboxylic acid, 3-(2-pyridinylthio)-, 1,1-dimethylethyl ester, (3R)-; (R)-1-(tert-Butoxycarbonyl)-3-(pyridin-2-ylthio)pyrrolidine
EINECS	Contact for details

Quality Control

Our (R)-3-(Pyridin-2-Ylsulfanyl)-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with stringent industry standards for pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.