Description

(R)-1-([1,2,4]Triazolo[4,3-A]Pyridin-3-Yl)Ethanamine is a high-purity chiral amine building block of significant interest in advanced organic synthesis. Its value lies in its unique fused triazolopyridine scaffold, which serves as a privileged structure for modulating biological activity and physicochemical properties in drug discovery. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and medicinal chemistry.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes to study enzyme function and receptor interactions.
• Agrochemical Research: Employed in the discovery of novel crop protection agents with enhanced selectivity.
• Material Science: Potential precursor for functionalized heterocyclic compounds used in advanced materials.

Basic Information

Product Name	(R)-1-([1,2,4]Triazolo[4,3-A]Pyridin-3-Yl)Ethanamine
CAS No.	1217810-82-6
Molecular Formula	C8H9N5
Molecular Weight	175.19 g/mol
Synonyms	(R)-1-(1,2,4-Triazolo[4,3-a]pyridin-3-yl)ethanamine; (R)-1-(1,2,4-Triazolo[4,3-a]pyridin-3-yl)ethan-1-amine; (R)-1-(1,2,4-Triazolo[4,3-a]pyridin-3-yl)ethylamine; (R)-1-(Triazolo[4,3-a]pyridin-3-yl)ethanamine; (R)-3-(1-Aminoethyl)-[1,2,4]triazolo[4,3-a]pyridine; (R)-α-Methyl[1,2,4]triazolo[4,3-a]pyridine-3-ethanamine
EINECS	Contact for details

Quality Control

Our (R)-1-([1,2,4]Triazolo[4,3-A]Pyridin-3-Yl)Ethanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.