Description

4-(5-{[(2R,6S)-2,6-Dimethylmorpholin-4-Yl]Methyl}-1,2,4-Oxadiazol-3-Yl)Benzaldehyde Hydrochloride is a high-purity, chiral organic building block of significant interest in advanced pharmaceutical research and development. This compound matters as a key synthetic intermediate, enabling the construction of complex molecules with specific stereochemistry for targeted biological activity. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries working on novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of potential active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to explore new chemical entities.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes for clinical trial material and commercial manufacturing.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function and biological pathways due to its specific morpholine-oxadiazole scaffold.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.
• Academic Research: Employed in university and institutional labs for methodological development in asymmetric synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-(5-{[(2R,6S)-2,6-Dimethylmorpholin-4-Yl]Methyl}-1,2,4-Oxadiazol-3-Yl)Benzaldehyde Hydrochloride
CAS No.	1217788-40-3
Molecular Formula	C₁₆H₂₀N₃O₂·HCl
Molecular Weight	323.81 g/mol (Free base: 286.35 g/mol)
Synonyms	4-(5-(((2R,6S)-2,6-Dimethylmorpholino)methyl)-1,2,4-oxadiazol-3-yl)benzaldehyde hydrochloride; (2R,6S)-4-((3-(4-Formylphenyl)-1,2,4-oxadiazol-5-yl)methyl)-2,6-dimethylmorpholine hydrochloride; 4-[5-[[(2R,6S)-2,6-Dimethyl-4-morpholinyl]methyl]-1,2,4-oxadiazol-3-yl]-benzaldehyde HCl; Benzaldehyde, 4-[5-[[(2R,6S)-2,6-dimethyl-4-morpholinyl]methyl]-1,2,4-oxadiazol-3-yl]-, hydrochloride; UNII-8K6H9Q4K1F; 8K6H9Q4K1F
EINECS	Contact for details

Quality Control

Our 4-(5-{[(2R,6S)-2,6-Dimethylmorpholin-4-Yl]Methyl}-1,2,4-Oxadiazol-3-Yl)Benzaldehyde Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent oxidation and moisture uptake. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.