Description

(R)-3-Bromo-4,4-Dimethyldihydrofuran-2-One is a high-value chiral building block and synthetic intermediate of significant interest in advanced organic synthesis. Its core value lies in its stereodefined structure and reactive bromine substituent, which enable the efficient construction of complex, optically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Research: Used in the development of novel, stereospecific pesticides and herbicides where biological activity is often enantiomer-dependent.
• Asymmetric Synthesis: Serves as a versatile precursor in catalytic asymmetric reactions to introduce chiral lactone or functionalized furanone motifs.
• Material Science: Potential monomer or intermediate for creating specialized polymers with unique optical or electronic properties.
• Academic & Process R&D: Employed in methodological studies and scale-up process development for complex organic molecules.

Basic Information

Product Name	(R)-3-Bromo-4,4-Dimethyldihydrofuran-2-One
CAS No.	1217724-84-9
Molecular Formula	C6H9BrO2
Molecular Weight	193.04 g/mol
Synonyms	(R)-3-Bromo-4,4-dimethyl-2(3H)-furanone; (3R)-3-Bromo-4,4-dimethyl-2,5-dihydrofuran-2-one; (R)-3-Bromo-4,4-dimethylbutyrolactone; (R)-3-Bromo-4,4-dimethyl-dihydro-2(3H)-furanone; (R)-3-Bromo-4,4-dimethyl-2-oxotetrahydrofuran; (R)-3-Bromo-4,4-dimethyl-γ-butyrolactone; (R)-3-Bromo-4,4-dimethyl-γ-lactone
EINECS	Contact for details

Quality Control

Our (R)-3-Bromo-4,4-Dimethyldihydrofuran-2-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and chiral purity, meeting the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.