Description

Rac-Trans 3’-Acetylthiomethyl Nicotine is a chemically modified nicotine derivative, identified by CAS number 1217716-10-3, designed for advanced research and synthesis applications. This compound serves as a critical intermediate for developing novel nicotine analogs and studying nicotinic acetylcholine receptor interactions. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and specialized chemical manufacturers focused on alkaloid chemistry and receptor-targeted drug discovery.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel nicotinic receptor ligands and potential therapeutic agents.
• Neuroscience Research: Used in biochemical studies to investigate the structure-activity relationships (SAR) of nicotine derivatives at receptor sites.
• Agrochemical Development: Serves as a precursor in the research of novel neonicotinoid-inspired compounds for crop protection.
• Chemical Synthesis: A versatile intermediate for organic chemists exploring sulfur-containing alkaloid modifications.
• Reference Standard: Employed as an analytical standard in quality control and method development for nicotine-related product analysis.
• Metabolite Studies: Useful in the research of nicotine metabolism and the identification of potential biomarkers.

Basic Information

Item	Details
Product Name	Rac-Trans 3’-Acetylthiomethyl Nicotine
CAS No.	1217716-10-3
Molecular Formula	C13H18N2OS
Molecular Weight	250.36 g/mol
Synonyms	3'-[(Acetylthio)methyl]nicotine (racemic trans isomer); (Rac)-trans-3'-(Acetylthiomethyl)nicotine; Nicotine, 3'-(acetylthiomethyl)-, trans-(±)-; 1-Methyl-2-(3-pyridyl)pyrrolidine-3-spiro-2'-(1',3'-thiazolidine)-4'-one (related structure); 3'-Acetylthiomethylnicotine; trans-3'-Acetylthiomethylnicotine (racemic); (±)-trans-3'-(Acetylthiomethyl)nicotine
EINECS	Contact for details

Quality Control

Our Rac-Trans 3’-Acetylthiomethyl Nicotine is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets exacting research-grade specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.