Description

1-Piperidinecarboxylic Acid, 2-(1-Methylethyl)-4-Oxo-, 1,1-Dimethylethyl Ester, (2R)- is a high-purity, chiral piperidine derivative, a critical advanced intermediate in modern pharmaceutical synthesis. Its value lies in its role as a sophisticated building block for constructing complex active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system and other therapeutic areas. This compound is essential for research institutions and pharmaceutical manufacturers engaged in the development and scale-up of novel, optically active drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex, biologically active molecules and Active Pharmaceutical Ingredients (APIs).
• Protease Inhibitor Research: Used in the development of inhibitors for various proteolytic enzymes, relevant for antiviral and anticancer drug discovery.
• Asymmetric Synthesis: Serves as a valuable starting material or intermediate in stereoselective chemical transformations to introduce the chiral 2-isopropylpiperidine motif.
• Neurological & CNS Drug Development: Applied in the research and production of compounds targeting neurological disorders, pain management, and psychiatric conditions.
• Process Chemistry & Scale-Up: Supplied in development and commercial quantities to support route scouting, optimization, and cGMP manufacturing campaigns.
• Contract Research & Manufacturing (CRO/CMO): A critical raw material for organizations providing custom synthesis and manufacturing services to the pharmaceutical industry.

Basic Information

Product Name	1-Piperidinecarboxylic Acid, 2-(1-Methylethyl)-4-Oxo-, 1,1-Dimethylethyl Ester, (2R)-
CAS No.	1217662-38-8
Molecular Formula	C13H23NO3
Molecular Weight	241.33 g/mol
Synonyms	(2R)-2-Isopropyl-4-oxopiperidine-1-carboxylic acid tert-butyl ester; tert-Butyl (2R)-2-isopropyl-4-oxopiperidine-1-carboxylate; (R)-tert-Butyl 2-isopropyl-4-oxopiperidine-1-carboxylate; (R)-N-Boc-2-isopropyl-4-piperidone; (2R)-2-(Propan-2-yl)-4-oxopiperidine-1-carboxylic acid tert-butyl ester; (R)-1-Boc-2-isopropyl-4-piperidone; BOC-(R)-2-Isopropyl-4-piperidone
EINECS	Contact for details

Quality Control

Our production of 1-Piperidinecarboxylic Acid, 2-(1-Methylethyl)-4-Oxo-, 1,1-Dimethylethyl Ester, (2R)- adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting pharmaceutical-grade standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.