Description

n-Boc-4-[Bis(2-Hydroxyethyl)Amino]-L-Phenylalanine Methyl Ester is a protected amino acid derivative of significant value in advanced organic synthesis. This compound serves as a crucial building block for the preparation of complex peptides and peptidomimetics, offering a versatile handle for further functionalization. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and biochemical probes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to introduce a modified phenylalanine residue with a protected amine and polar side chain.
• Bioconjugation: Serves as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology: Employed in the design and synthesis of enzyme inhibitors, receptor ligands, and fluorescent probes for biological studies.
• Material Science: Potential monomer for creating functionalized polymers with specific biological recognition properties.

Basic Information

Product Name	n-Boc-4-[Bis(2-Hydroxyethyl)Amino]-L-Phenylalanine Methyl Ester
CAS No.	1217651-06-3
Molecular Formula	C21H32N2O7
Molecular Weight	424.49 g/mol
Synonyms	Boc-4-[Bis(2-hydroxyethyl)amino]-L-Phe-OMe; (S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-(4-(bis(2-hydroxyethyl)amino)phenyl)propanoate; tert-Butyl (S)-1-((4-(bis(2-hydroxyethyl)amino)phenyl)-1-methoxy-1-oxopropan-2-yl)carbamate; L-Phenylalanine, 4-[bis(2-hydroxyethyl)amino]-, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester; Boc-DEAE-L-Phe-OMe; N-Boc-4-(N,N-diethanolamino)-L-phenylalanine methyl ester
EINECS	Contact for details

Quality Control

Our n-Boc-4-[Bis(2-Hydroxyethyl)Amino]-L-Phenylalanine Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere to prevent decomposition. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.