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3-(6-Amino-Pyridin-2-Yl)-n-Boc-D-Alanine CAS NO 1217630-85-7


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CAS No.:1217630-85-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-(6-Amino-Pyridin-2-Yl)-n-Boc-D-Alanine is a sophisticated, non-natural amino acid derivative designed for advanced pharmaceutical research and development. This compound serves as a critical chiral building block for the synthesis of complex peptides and peptidomimetics, offering precise control over molecular architecture. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for creating novel therapeutic candidates, particularly in targeted drug discovery programs.

Application

  • Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for peptide-based therapeutics.
  • Peptidomimetic Drug Discovery: Used to construct peptide analogs with enhanced metabolic stability, bioavailability, and receptor selectivity.
  • Protease Inhibitor Synthesis: Incorporated into the backbone of potential inhibitors for various proteolytic enzymes.
  • Chemical Biology Tool: Employed in the synthesis of labeled peptides or probes for studying protein-protein interactions and enzyme mechanisms.
  • Combinatorial Chemistry: Serves as a valuable building block in solid-phase and solution-phase peptide library synthesis for high-throughput screening.
  • Agrochemical Research: Potential intermediate in the development of novel, biologically active compounds for crop protection.

Basic Information

Product Name 3-(6-Amino-Pyridin-2-Yl)-n-Boc-D-Alanine
CAS No. 1217630-85-7
Molecular Formula C13H19N3O4
Molecular Weight 281.31 g/mol
Synonyms N-(tert-Butoxycarbonyl)-3-(6-aminopyridin-2-yl)-D-alanine; Boc-D-Ala(6-Amino-2-Pyridyl)-OH; (2R)-2-[[(2-Methylpropan-2-yl)oxycarbonyl]amino]-3-(6-aminopyridin-2-yl)propanoic acid; 3-(6-Amino-2-pyridinyl)-N-[(1,1-dimethylethoxy)carbonyl]-D-alanine; tert-Butyl (R)-(1-(6-aminopyridin-2-yl)-2-carboxyethyl)carbamate; Boc-D-3-(6-Amino-2-Pyridyl)alanine
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Quality Control

Our 3-(6-Amino-Pyridin-2-Yl)-n-Boc-D-Alanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC/MS) Conforms
Identification (IR) Conforms
Purity (HPLC) ≥ 97.0%
Chiral Purity (Chiral HPLC) ≥ 99.0% ee
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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