Description

(2S,5R)-5-(4-Bromo-Benzyl)-Piperidine-1,2-Dicarboxylic Acid 1-tert-Butyl Ester is a high-purity, chiral piperidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its defined stereochemistry and protected functional groups, which enable precise and efficient construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides where specific chirality impacts biological activity.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for commercial production of complex molecules.
• Catalyst & Ligand Development: Acts as a precursor for synthesizing novel chiral catalysts and ligands used in asymmetric synthesis.
• Reference Standard: Provides a high-purity standard for analytical method development and quality control in regulated industries.

Basic Information

Product Name	(2S,5R)-5-(4-Bromo-Benzyl)-Piperidine-1,2-Dicarboxylic Acid 1-tert-Butyl Ester
CAS No.	1217625-05-2
Molecular Formula	C19H26BrNO4
Molecular Weight	412.32 g/mol
Synonyms	1-(1,1-Dimethylethyl) (2S,5R)-5-[(4-Bromophenyl)methyl]-1,2-piperidinedicarboxylate; tert-Butyl (2S,5R)-5-[(4-Bromophenyl)methyl]piperidine-1,2-dicarboxylate; (2S,5R)-5-(4-Bromobenzyl)piperidine-1,2-dicarboxylic acid 1-tert-butyl ester; 5-(4-Bromo-benzyl)-piperidine-1,2-dicarboxylic acid 1-tert-butyl ester (2S,5R)-; CAS 1217625-05-2; Boc-protected bromobenzyl piperidine dicarboxylate
EINECS	Contact for details

Quality Control

Our production of (2S,5R)-5-(4-Bromo-Benzyl)-Piperidine-1,2-Dicarboxylic Acid 1-tert-Butyl Ester adheres to stringent quality management systems, ensuring batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to meet the exacting standards required for pharmaceutical R&D and cGMP applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.