Description

(3Ar,7As)-2-tert-Butyl 7A-Ethyl Hexahydro-1H-Pyrrolo[3,4-C]Pyridine-2,7A(3H)-Dicarboxylate CAS NO 1217622-72-4 is a high-purity, advanced pharmaceutical intermediate featuring a complex, rigid bicyclic scaffold. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with enhanced target specificity and metabolic stability. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) therapeutics, enzyme inhibitors, and other biologically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• CNS Drug Development: Serves as a core structure in the synthesis of potential neuropsychiatric and neurological disorder treatments.
• Enzyme Inhibitor Synthesis: Employed in creating novel protease or kinase inhibitors for targeted therapies.
• Chemical Biology Probes: Utilized to develop tool compounds for investigating biological pathways and protein functions.
• Asymmetric Synthesis: Acts as a chiral auxiliary or precursor in stereoselective chemical transformations.

Basic Information

Product Name	(3Ar,7As)-2-tert-Butyl 7A-Ethyl Hexahydro-1H-Pyrrolo[3,4-C]Pyridine-2,7A(3H)-Dicarboxylate
CAS No.	1217622-72-4
Molecular Formula	C16H28N2O4
Molecular Weight	312.41 g/mol
Synonyms	2-(tert-Butoxycarbonyl)-7a-ethylhexahydro-1H-pyrrolo[3,4-c]pyridine-7a(3H)-carboxylic acid; tert-Butyl 7a-ethyl-2,3,3a,4,6,7-hexahydro-1H-pyrrolo[3,4-c]pyridine-2-carboxylate; (3aR,7aS)-2-tert-Butyl 7a-ethyl hexahydro-1H-pyrrolo[3,4-c]pyridine-2,7a(3H)-dicarboxylate; BOC-Protected 7a-ethyl hexahydro-1H-pyrrolo[3,4-c]pyridine; 7a-Ethyl-1,2,3,3a,4,6,7,7a-octahydropyrrolo[3,4-c]pyridine-2,7a-dicarboxylic acid 2-tert-butyl ester
EINECS	Contact for details

Quality Control

Our (3Ar,7As)-2-tert-Butyl 7A-Ethyl Hexahydro-1H-Pyrrolo[3,4-C]Pyridine-2,7A(3H)-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.