Description

(5-Chloro-6-Fluoropyridin-3-Yl)Methanol is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents adjacent to a hydroxymethyl group, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	(5-Chloro-6-Fluoropyridin-3-Yl)Methanol
CAS No.	1217554-18-1
Molecular Formula	C6H5ClFNO
Molecular Weight	161.56 g/mol
Synonyms	3-(Hydroxymethyl)-5-chloro-6-fluoropyridine; 5-Chloro-6-fluoro-3-pyridinemethanol; (5-Chloro-6-fluoro-3-pyridinyl)methanol; 5-Chloro-6-fluoronicotinyl alcohol; 5-Chloro-6-fluoro-3-hydroxymethylpyridine; 3-Pyridinemethanol, 5-chloro-6-fluoro-; 5-Chloro-6-fluoropyridine-3-methanol
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Production batches of (5-Chloro-6-Fluoropyridin-3-Yl)Methanol are analyzed using advanced techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. Our quality system supports compliance with cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.