Description

2'-Benzyl-1'-Oxo-1',4'-Dihydro-2'H-Spiro[Cyclo-Pentane-1,3'-Isoquinoline]-4'-Carboxylic Acid is a sophisticated spirocyclic organic compound that serves as a critical building block in advanced chemical synthesis. Its unique molecular architecture, featuring a fused isoquinoline and cyclopentane ring system, makes it a valuable intermediate for pharmaceutical research and development. This high-purity compound is primarily utilized by R&D chemists and process development scientists in the life sciences sector to create novel therapeutic agents and explore new chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its complex, drug-like spirocyclic scaffold.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) guidelines.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and reference standards.
• Academic Research: Employed in university and institutional laboratories for pioneering research in organic synthesis methodology and heterocyclic chemistry.

Basic Information

Product Name	2'-Benzyl-1'-Oxo-1',4'-Dihydro-2'H-Spiro[Cyclo-Pentane-1,3'-Isoquinoline]-4'-Carboxylic Acid
CAS No.	1217531-04-8
Molecular Formula	C21H19NO3
Molecular Weight	333.38 g/mol
Synonyms	2'H-Spiro[cyclopentane-1,3'-isoquinoline]-4'-carboxylic acid, 2'-benzyl-1',4'-dihydro-1'-oxo-; 2'-Benzyl-1-oxo-1,4-dihydro-2'H-spiro[cyclopentane-1,3'-isoquinoline]-4'-carboxylic acid; Spiro[cyclopentane-1,3'-isoquinoline]-4'-carboxylic acid, 2'-benzyl-1',4'-dihydro-1'-oxo-; 1217531-04-8; Benzyl-spiro-isoquinoline-carboxylic acid derivative; CAS 1217531-04-8
EINECS	Contact for details

Quality Control

Our 2'-Benzyl-1'-Oxo-1',4'-Dihydro-2'H-Spiro[Cyclo-Pentane-1,3'-Isoquinoline]-4'-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment aligns with ICH guidelines, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.