Description

(R)-3-n-Boc-Amino-1-[2-Amino-1-(2-Chloro-Phenyl)-Ethyl]-Pyrrolidine is a high-purity, chiral pyrrolidine derivative serving as a critical advanced pharmaceutical intermediate (API) and building block in organic synthesis. Its value lies in its complex stereochemistry and functional groups, which are essential for constructing sophisticated molecules with specific biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and receptor-targeted therapies.

Application

• Pharmaceutical Intermediate: Key chiral building block in the synthesis of novel drug candidates, especially for neurological and psychiatric disorders.
• Asymmetric Synthesis: Used as a ligand or precursor in catalytic asymmetric reactions to induce chirality in target molecules.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Peptidomimetics Development: Serves as a constrained scaffold to mimic peptide structures, enhancing metabolic stability and bioavailability.
• Chemical Biology Probes: Utilized in the creation of molecular probes to study enzyme function and receptor interactions.
• Custom Synthesis: A starting material for the contract manufacturing of complex, high-value specialty chemicals.

Basic Information

Product Name	(R)-3-n-Boc-Amino-1-[2-Amino-1-(2-Chloro-Phenyl)-Ethyl]-Pyrrolidine
CAS No.	1217517-98-0
Molecular Formula	C₁₇H₂₆ClN₃O₂
Molecular Weight	339.86 g/mol
Synonyms	(R)-1-[2-Amino-1-(2-chlorophenyl)ethyl]-3-[(tert-butoxycarbonyl)amino]pyrrolidine; tert-Butyl N-[(3R)-1-[2-amino-1-(2-chlorophenyl)ethyl]pyrrolidin-3-yl]carbamate; (R)-3-(Boc-amino)-1-[2-amino-1-(2-chlorophenyl)ethyl]pyrrolidine; (R)-3-(tert-Butoxycarbonylamino)-1-[2-amino-1-(2-chlorophenyl)ethyl]pyrrolidine; BOC-(R)-Amino Chlorophenyl Ethyl Pyrrolidine; (R)-3-N-Boc-Amino-1-(2-Amino-1-(2-Chloro-Phenyl)-Ethyl)-Pyrrolidine; (R)-3-(Boc-NH)-1-[2-NH2-1-(2-Cl-Ph)-Et]-Pyrrolidine
EINECS	Contact for details

Quality Control

Our (R)-3-n-Boc-Amino-1-[2-Amino-1-(2-Chloro-Phenyl)-Ethyl]-Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and NMR for structural confirmation, to ensure compliance with high-purity research and pharmaceutical grade standards. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.