Description

n-Boc-10-Azidodecan-1-Amine is a bifunctional organic building block featuring both a protected amine and a terminal azide group. This compound is essential for advanced bioconjugation and click chemistry applications, enabling the precise and efficient formation of stable linkages. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and materials science sectors for developing novel therapeutics, diagnostic probes, and functional polymers.

Application

• Bioconjugation Reagent: Used for site-specific labeling of proteins, antibodies, and other biomolecules via copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry.
• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of antibody-drug conjugates (ADCs), targeted drug delivery systems, and novel active pharmaceutical ingredients (APIs).
• Polymer Functionalization: Enables the introduction of amine-reactive sites onto polymer backbones or surfaces for creating smart materials and hydrogels.
• Probe Synthesis: Facilitates the development of fluorescent, radioactive, or affinity tags for cellular imaging and diagnostic assays.
• Peptide and Protein Modification: Allows for the controlled modification of peptides and proteins to study function or enhance stability.
• Crosslinking Agent: Acts as a heterobifunctional crosslinker for coupling different molecules or materials in biomanufacturing and nanotechnology.
• Chemical Biology Tool: Employed in activity-based protein profiling (ABPP) and other chemoproteomic strategies to explore enzyme function and discover new drug targets.
• Material Science Research: Used to create functionalized surfaces, nanoparticles, and dendrimers with tailored biological activity.

Basic Information

Product Name	n-Boc-10-Azidodecan-1-Amine
CAS No.	1217362-05-4
Molecular Formula	C15H30N4O2
Molecular Weight	298.43 g/mol
Synonyms	10-Azido-1-[(tert-butoxycarbonyl)amino]decane; 1-Amino-10-azidodecane tert-butylcarbamate; Boc-10-azidodecylamine; N-(10-Azidodecyl)-N-Boc-amine; tert-Butyl (10-azidodecyl)carbamate; N-Boc-1,10-diaminodecane azide; Azido-PEG10-amine Boc-protected; 10-Azidodecan-1-amine, N-Boc-protected
EINECS	Contact for details

Quality Control

Our n-Boc-10-Azidodecan-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FT-IR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific research or cGMP guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under inert atmosphere for long-term stability. This material is light-sensitive and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.