Description

5-Cyano-6-Methylnicotinic Acid is a high-purity, versatile pyridine derivative and a key synthetic intermediate in advanced organic chemistry. Its core value lies in its functionalized structure, which provides a crucial scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists working on active pharmaceutical ingredients (APIs), novel agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and diagnostic agents due to its modifiable cyano and carboxylic acid groups.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Cyano-6-Methylnicotinic Acid
CAS No.	1216866-96-4
Molecular Formula	C8H6N2O2
Molecular Weight	162.15 g/mol
Synonyms	6-Methyl-5-cyanonicotinic Acid; 5-Cyano-6-methylpyridine-3-carboxylic Acid; 3-Pyridinecarboxylic acid, 5-cyano-6-methyl-; 6-Methyl-5-cyano-3-pyridinecarboxylic Acid; 5-Cyano-6-methyl-3-pyridinecarboxylic Acid; 6-Methyl-5-cyanopyridine-3-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 5-Cyano-6-Methylnicotinic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.