Description

2-Azido-1-(Chloromethyl)Ethyl Carbonic Acid Phenyl Ester is a specialized bifunctional organic building block containing both an azide and a chloromethyl group. This compound is highly valued in advanced organic synthesis for its role as a versatile intermediate in click chemistry and polymer cross-linking applications. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and materials science sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and bioconjugates via copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry.
• Polymer Chemistry: Serves as a cross-linking agent and functional monomer for modifying polymer backbones, introducing azide functionalities for subsequent grafting or labeling.
• Bioconjugation & Probe Development: Used to attach fluorescent dyes, affinity tags, or other reporter molecules to biomolecules like proteins, peptides, or oligonucleotides.
• Agrochemical Research: Intermediate in the development of new crop protection agents and herbicides with tailored properties.
• Materials Science: Building block for creating functionalized surfaces, hydrogels, and smart materials with responsive characteristics.
• Chemical Biology Tool: Enables site-specific labeling and study of biological processes within living systems.

Basic Information

Product Name	2-Azido-1-(Chloromethyl)Ethyl Carbonic Acid Phenyl Ester
CAS No.	1216552-75-8
Molecular Formula	C10H10ClN3O3
Molecular Weight	255.66 g/mol
Synonyms	Phenyl (2-azido-1-(chloromethyl)ethoxy)formate; 1-Chloromethyl-2-azidoethyl phenyl carbonate; Azidomethyl chloromethyl ethyl phenyl carbonate; Carbonic acid, 2-azido-1-(chloromethyl)ethyl phenyl ester; (2-Azido-1-chloromethylethyl) phenyl carbonate; 2-Azido-1-chloromethyl ethyl phenyl carbonate
EINECS	Contact for details

Quality Control

Our 2-Azido-1-(Chloromethyl)Ethyl Carbonic Acid Phenyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FT-IR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate to maximize shelf-life stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.