Description

3-Amino-2-Chloro-6-Methoxypyridine, Hcl is a high-purity, halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring amino, chloro, and methoxy substituents, makes it a versatile intermediate for constructing complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, especially those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with specific modes of action.
• Material Science Research: Used in the development of organic semiconductors, ligands for catalysis, and specialty polymers.
• Chemical Research & Development: A valuable scaffold for medicinal chemistry and process chemistry for exploring new chemical entities.
• Dye & Pigment Intermediate: Serves in the synthesis of specialized colorants and functional dyes.

Basic Information

Product Name	3-Amino-2-Chloro-6-Methoxypyridine, Hcl
CAS No.	1216499-22-7
Molecular Formula	C6H8ClN2O•HCl
Molecular Weight	195.05 g/mol (Free base: 158.59 g/mol)
Synonyms	2-Chloro-6-methoxy-3-pyridinamine hydrochloride; 3-Amino-2-chloro-6-methoxypyridine hydrochloride; 2-Chloro-6-methoxypyridin-3-amine hydrochloride; 6-Methoxy-2-chloropyridin-3-amine hydrochloride; 3-Pyridinamine, 2-chloro-6-methoxy-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 3-Amino-2-Chloro-6-Methoxypyridine, Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.