Description

5-Amino-3-Bromo-2-Piperidinopyridine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring both amino and bromo substituents on a pyridine core fused with a piperidine ring, makes it a versatile intermediate for constructing complex pharmacophores. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially for neurological targets, kinase inhibitors, and receptor modulators.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Chemical Biology & Proteomics: Serves as a scaffold or linker for designing molecular probes and tool compounds to study biological pathways.
• Material Science: Potential building block for advanced organic electronic materials and ligands in catalytic systems.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and process development projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and organohalogen chemistry.

Basic Information

Product Name	5-Amino-3-Bromo-2-Piperidinopyridine
CAS No.	1216080-18-0
Molecular Formula	C10H14BrN3
Molecular Weight	256.15 g/mol
Synonyms	3-Bromo-5-amino-2-piperidinopyridine; 2-Piperidinopyridine, 5-amino-3-bromo-; 5-Amino-3-bromo-2-(piperidin-1-yl)pyridine; 1216080-18-0; 3-Bromo-2-piperidin-1-ylpyridin-5-amine; 5-Amino-3-bromo-2-(1-piperidinyl)pyridine
EINECS	Contact for details

Quality Control

Every batch of 5-Amino-3-Bromo-2-Piperidinopyridine is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.