Description

2-(Oxan-4-Ylmethoxy)Pyridine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing next-generation small-molecule drugs and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides that require specific pyridine-carboxylic acid motifs for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and functional polymers due to its conjugated system.
• Chemical Biology Probes: Utilized as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	2-(Oxan-4-Ylmethoxy)Pyridine-4-Carboxylic Acid
CAS No.	1215846-28-8
Molecular Formula	C12H15NO4
Molecular Weight	237.25 g/mol
Synonyms	4-Pyridinecarboxylic acid, 2-[(tetrahydro-2H-pyran-4-yl)oxy]-; 2-((Tetrahydro-2H-pyran-4-yl)oxy)isonicotinic acid; 2-(Oxan-4-ylmethoxy)pyridine-4-carboxylic acid; 2-(Tetrahydropyran-4-ylmethoxy)isonicotinic acid; 2-[(Oxan-4-yl)methoxy]pyridine-4-carboxylic acid; 1215846-28-8; 2-(Oxan-4-Ylmethoxy)Pyridine-4-Carboxylic Acid; 2-(Tetrahydro-2H-pyran-4-ylmethoxy)isonicotinic acid
EINECS	Contact for details

Quality Control

Our 2-(Oxan-4-Ylmethoxy)Pyridine-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets stringent specifications for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support compliance with relevant regulatory frameworks including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.