Description

2-Azaspiro[5.5]undecan-1-one (Saltdata: Free) is a high-purity, specialized organic building block featuring a unique spirocyclic lactam structure. This compound is valued for its rigid, three-dimensional framework, which is critical for modulating the physicochemical properties and biological activity of advanced molecules. It serves as a key synthetic intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients. The free base form, with CAS number 1215295-79-6, offers versatility for further chemical modifications.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, especially for central nervous system (CNS) targets, protease inhibitors, and other therapeutic agents requiring complex, spirocyclic scaffolds.
• Agrochemical Research: Used in the design and development of new generation pesticides and herbicides, where its structural rigidity can contribute to improved stability and target specificity.
• Chemical Biology & Proteomics: Employed as a specialty scaffold or linker in the creation of chemical probes, activity-based probes (ABPs), and fragment-based drug discovery libraries.
• Material Science Research: Investigated as a monomer or precursor for constructing polymers with specific thermal or mechanical properties due to its constrained geometry.
• Academic & Contract Research: Serves as a valuable starting material for methodological studies in organic synthesis, particularly in spirocycle formation and functionalization.

Basic Information

Item	Details
Product Name	2-Azaspiro[5.5]undecan-1-one (Saltdata: Free)
CAS No.	1215295-79-6
Molecular Formula	C10H17NO
Molecular Weight	167.25 g/mol
Synonyms	1-Azaspiro[5.5]undecan-2-one; 2-Azaspiro[5.5]undecan-1-one; Spiro[cyclohexane-1,3'-pyrrolidin]-2'-one; 1-Oxo-2-azaspiro[5.5]undecane; 2-Azaspiro[5.5]undecanone; 2-Azaspiro[5.5]undecan-1-one free base; Lactam, spirocyclic C10
EINECS	Contact for details

Quality Control

Our 2-Azaspiro[5.5]undecan-1-one (Saltdata: Free) is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, which includes data from HPLC, GC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.