Description

Ethyl 2-(3-Chloro-2-Methylphenyl)-2,2-Difluoroacetate is a high-purity fluorinated organic building block of significant interest in advanced chemical synthesis. Its core value lies in its unique difluoroacetate ester structure, which serves as a versatile intermediate for introducing the difluoromethyl or difluoroacetyl group into complex molecules. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates containing difluoromethyl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the difluoroacetate group enhances biological activity.
• Material Science Research: Serves as a precursor for specialty monomers or ligands used in catalysis and polymer development.
• Organic Synthesis & Process Chemistry: A versatile reagent for constructing complex carbon skeletons in medicinal and process chemistry laboratories.
• Fluorine Chemistry Studies: Essential for academic and industrial research focused on the properties and reactivities of organofluorine compounds.

Basic Information

Product Name	Ethyl 2-(3-Chloro-2-Methylphenyl)-2,2-Difluoroacetate
CAS No.	1215205-45-0
Molecular Formula	C11H11ClF2O2
Molecular Weight	248.65 g/mol
Synonyms	Ethyl 3-Chloro-2-methyl-α,α-difluorobenzeneacetate; 2-(3-Chloro-2-methylphenyl)-2,2-difluoroacetic Acid Ethyl Ester; Ethyl (3-Chloro-2-methylphenyl)difluoroacetate; Ethyl 2,2-Difluoro-2-(3-chloro-2-methylphenyl)acetate; 1215205-45-0; Acetic acid, 2-(3-chloro-2-methylphenyl)-2,2-difluoro-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-(3-Chloro-2-Methylphenyl)-2,2-Difluoroacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.