Description

3-Bromo-1-Methyl-5-(Trifluoromethyl)Pyridin-2(1H)-One is a high-value, multi-functional heterocyclic building block characterized by its bromine and trifluoromethyl substituents. This compound is essential for facilitating advanced molecular construction in pharmaceutical and agrochemical research, offering versatile reactivity for cross-coupling and functional group transformations. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for the synthesis of novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for functionalized ligands and organic electronic materials due to its unique electronic properties.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to form complex biaryl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	3-Bromo-1-Methyl-5-(Trifluoromethyl)Pyridin-2(1H)-One
CAS No.	1215205-35-8
Molecular Formula	C7H5BrF3NO
Molecular Weight	256.02 g/mol
Synonyms	3-Bromo-1-methyl-5-(trifluoromethyl)pyridin-2(1H)-one; 3-Bromo-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone; 2(1H)-Pyridinone, 3-bromo-1-methyl-5-(trifluoromethyl)-; 3-Bromo-1-methyl-5-(trifluoromethyl)-1,2-dihydropyridin-2-one; 3-Bromo-1-methyl-5-trifluoromethyl-2(1H)-pyridone; 3-Bromo-1-methyl-5-(trifluoromethyl)-2-pyridone
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-1-Methyl-5-(Trifluoromethyl)Pyridin-2(1H)-One is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.