Description

1-(4-Nitrophenyl)-Cyclobutanecarboxylic Acid Methyl Ester is a specialized organic building block featuring a cyclobutane ring and a nitrophenyl group, making it a valuable intermediate for advanced chemical synthesis. Its unique structure provides a rigid scaffold and reactive handles for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists working on novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or inflammatory pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, where the cyclobutane core can impart favorable biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or precursor for advanced polymers and liquid crystals, leveraging its rigid, non-planar structure.
• Chemical Biology Probe: Utilized in the design of molecular probes and enzyme inhibitors for biochemical and pharmacological studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing high-value, low-volume specialty chemicals.
• Academic Research: Employed in university and institutional labs for methodological development in organic chemistry, such as studies on ring strain or photochemical reactions.

Basic Information

Product Name	1-(4-Nitrophenyl)-Cyclobutanecarboxylic Acid Methyl Ester
CAS No.	1215103-48-2
Molecular Formula	C12H13NO4
Molecular Weight	235.24 g/mol
Synonyms	Methyl 1-(4-nitrophenyl)cyclobutanecarboxylate; 1-(4-Nitrophenyl)cyclobutanecarboxylic acid methyl ester; Cyclobutanecarboxylic acid, 1-(4-nitrophenyl)-, methyl ester; Methyl 1-(p-nitrophenyl)cyclobutanecarboxylate; 1-(p-Nitrophenyl)cyclobutanecarboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our 1-(4-Nitrophenyl)-Cyclobutanecarboxylic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a Certificate of Analysis (COA) with every shipment, detailing all critical quality attributes to ensure it meets your specific research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.