Description

3,3-Difluoro-Cyclobutyl Benzoate is a high-value fluorinated organic building block. This compound is critical for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in synthesizing complex molecules for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used to introduce the rigid, polar 3,3-difluorocyclobutyl moiety into lead compounds to modulate their pharmacokinetic properties.
• Agrochemical Development: Serves as a precursor in the creation of advanced pesticides and herbicides with enhanced efficacy.
• Ligand and Catalyst Synthesis: Employed in the preparation of specialized ligands for catalysis and materials science applications.
• Fluorine Chemistry Studies: A valuable substrate for investigating structure-activity relationships (SAR) influenced by fluorinated alicyclic rings.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	3,3-Difluoro-Cyclobutyl Benzoate
CAS No.	1215071-19-4
Molecular Formula	C11H10F2O2
Molecular Weight	212.19 g/mol
Synonyms	Benzoic Acid, 3,3-Difluorocyclobutyl Ester; 3,3-Difluorocyclobutyl Benzoate; 1-(Benzoyloxy)-3,3-difluorocyclobutane; Cyclobutanol, 3,3-difluoro-, benzoate; 1215071-19-4
EINECS	Contact for details

Quality Control

Our 3,3-Difluoro-Cyclobutyl Benzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.