Description

3-Fluoro-1-Oxa-8-Aza-Spiro[4.5]Decane (Wx100254) is a high-value, fluorinated spirocyclic building block with the CAS number 1214875-53-2. This compound is essential for medicinal chemistry and drug discovery programs, offering a unique three-dimensional scaffold that can significantly influence the pharmacokinetic and binding properties of lead molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Scaffold: Used to introduce conformational restraint and fluorine atoms into molecules to modulate potency, metabolic stability, and membrane permeability.
• Chemical Biology Probes: Serves as a core structure for developing tool compounds and probes to study biological targets and pathways.
• Agrochemical Research: Potential application in the development of new pesticides and herbicides, leveraging the spirocyclic and fluorine motifs.
• Material Science Precursor: Can be utilized in the research and development of advanced organic materials and ligands for catalysis.

Basic Information

Product Name	3-Fluoro-1-Oxa-8-Aza-Spiro[4.5]Decane (Wx100254)
CAS No.	1214875-53-2
Molecular Formula	C8H14FNO
Molecular Weight	159.20 g/mol
Synonyms	3-Fluoro-1-oxa-8-azaspiro[4.5]decane; 8-Aza-3-fluoro-1-oxaspiro[4.5]decane; 1-Oxa-8-aza-3-fluorospiro[4.5]decane; WX100254; WX-100254; Fluorinated spirocyclic amine ether; Spiro[4.5]decane, 3-fluoro-1-oxa-8-aza-
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-1-Oxa-8-Aza-Spiro[4.5]Decane is produced and tested under strict quality management protocols to ensure consistency and purity for critical research applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems support development under cGMP guidelines as required for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent degradation. Keep away from incompatible materials such as strong alkalis.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.