Description

3-(3-Fluoro-5-Methyl-Phenyl)-Pyridine is a high-purity fluorinated pyridine derivative, a key building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of pharmaceuticals and agrochemicals, where its unique fluorine-substituted aromatic structure imparts desirable biological activity and metabolic stability. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to innovate new active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances lipophilicity and target binding.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or fluorinated liquid crystals.
• Chemical Biology Probes: Utilized as a core structure for designing molecular probes and tags used in bioimaging and diagnostic assays.

Basic Information

Product Name	3-(3-Fluoro-5-Methyl-Phenyl)-Pyridine
CAS No.	1214389-86-2
Molecular Formula	C12H10FN
Molecular Weight	187.21 g/mol
Synonyms	3-(3-Fluoro-5-methylphenyl)pyridine; 3-(3-Fluoro-5-Methyl-Phenyl)Pyridine; 3-(3-Fluoro-5-methylphenyl)pyridine; 5'-Fluoro-3'-methyl-[1,1'-biphenyl]-3-carbonitrile (related structure); 3-Pyridyl-3-fluoro-5-methylbenzene; [1,1'-Biphenyl]-3-carbonitrile, 5'-fluoro-3'-methyl-; 3-(3-Fluoro-5-methylphenyl)pyridin
EINECS	Contact for details

Quality Control

Our 3-(3-Fluoro-5-Methyl-Phenyl)-Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical data are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.