Description

2-Chloro-6-(Trifluoromethyl)Benzoic Acid Methyl Ester is a high-value fluorinated aromatic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industrial and R&D chemists need it for constructing active ingredients, where the trifluoromethyl and chloro substituents impart desirable biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and bioactivity.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and as a substrate for further functionalization in medicinal chemistry research.
• Chemical Research & Development: A valuable standard and starting material in academic and industrial R&D labs for exploring new synthetic methodologies.

Basic Information

Product Name	2-Chloro-6-(Trifluoromethyl)Benzoic Acid Methyl Ester
CAS No.	1214386-37-4
Molecular Formula	C9H6ClF3O2
Molecular Weight	238.59 g/mol
Synonyms	Methyl 2-Chloro-6-(trifluoromethyl)benzoate; Benzoic acid, 2-chloro-6-(trifluoromethyl)-, methyl ester; 2-Chloro-α,α,α-trifluoro-o-toluic acid methyl ester; Methyl 2-chloro-α,α,α-trifluoro-o-toluate; 2-Chloro-6-trifluoromethylbenzoic acid methyl ester; o-Chloro-α,α,α-trifluorotoluic acid methyl ester; Methyl o-chloro-α,α,α-trifluorotoluate
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(Trifluoromethyl)Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.