Description

5-Bromo-6-Hydroxypicolinic Acid is a versatile heterocyclic building block and key synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scale-up synthesis.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other biologically active molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Ligand Synthesis: Serves as a starting material for creating complex chelating agents and catalysts in coordination chemistry.
• Material Science: Employed in the research and production of organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology: Utilized as a probe or tag in biochemical assays and for modifying biomolecules.
• Custom Synthesis: A key building block for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	5-Bromo-6-Hydroxypicolinic Acid
CAS No.	1214385-51-9
Molecular Formula	C6H4BrNO3
Molecular Weight	218.01 g/mol
Synonyms	6-Hydroxy-5-bromopyridine-2-carboxylic Acid; 5-Bromo-6-hydroxy-2-pyridinecarboxylic Acid; 5-Bromo-6-hydroxypicolinate; 2-Pyridinecarboxylic acid, 5-bromo-6-hydroxy-; 5-Bromo-6-hydroxypicolinic acid (CAS 1214385-51-9)
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Hydroxypicolinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.