Description

3,5-Dibromo-4-Iodopyridine is a highly functionalized halogenated pyridine derivative, serving as a critical multi-purpose building block in advanced organic synthesis. Its unique substitution pattern offers distinct reactivity for selective cross-coupling and nucleophilic substitution reactions, enabling the construction of complex molecular architectures. This compound is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogen sites for structural diversification.
• Material Science Building Block: Employed in the creation of organic electronic materials, ligands for catalysis, and liquid crystals due to its rigid, halogenated core.
• Cross-Coupling Reactions: Serves as an excellent substrate for Suzuki, Stille, and Negishi couplings, where the iodine and bromine atoms offer orthogonal reactivity.
• Nucleophilic Aromatic Substitution: Facilitates the introduction of nitrogen, oxygen, and sulfur nucleophiles to create diversely substituted pyridine scaffolds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems.

Basic Information

Product Name	3,5-Dibromo-4-Iodopyridine
CAS No.	1214383-75-1
Molecular Formula	C5H2Br2IN
Molecular Weight	402.79 g/mol
Synonyms	4-Iodo-3,5-dibromopyridine; 3,5-Dibromo-4-iodopyridine; Pyridine, 3,5-dibromo-4-iodo-; 4-Iodo-3,5-dibromopyridine; 1214383-75-1; SCHEMBL21806227; DTXSID90648169; BRN 12687047
EINECS	Contact for details

Quality Control

Our 3,5-Dibromo-4-Iodopyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.