Description

2,6-Dichloro-4-(Difluoromethoxy)Pyridine is a high-purity, halogenated pyridine derivative serving as a critical advanced intermediate in modern organic synthesis. Its unique structure, featuring both chloro and difluoromethoxy substituents, makes it a valuable building block for constructing complex molecules with tailored properties. This compound is primarily sought by R&D and production chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the difluoromethoxy group can enhance biological activity and metabolic stability.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized pyridine-based ligands used in catalysis and material science.
• Functional Material Development: Employed in the synthesis of organic electronic materials, such as components for OLEDs or charge-transport materials, due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2,6-Dichloro-4-(Difluoromethoxy)Pyridine
CAS No.	1214379-42-6
Molecular Formula	C6H3Cl2F2NO
Molecular Weight	214.00 g/mol
Synonyms	4-(Difluoromethoxy)-2,6-dichloropyridine; 2,6-Dichloro-4-(difluoromethoxy)pyridine; Pyridine, 2,6-dichloro-4-(difluoromethoxy)-; 1214379-42-6
EINECS	Contact for details

Quality Control

Every batch of 2,6-Dichloro-4-(Difluoromethoxy)Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the exacting standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.