Description

Ethyl 2-Chloro-3-Fluorobenzoate is a high-purity fluorinated aromatic ester building block of significant importance in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated and fluorinated motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the chloro-fluoro substitution pattern enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes.
• Functional Material Research: Employed in academic and industrial R&D for creating novel polymers, ligands, and specialty chemicals with tailored properties.
• Cross-Coupling Reactions: An effective substrate in palladium-catalyzed reactions like Suzuki-Miyaura and Buchwald-Hartwig amination for constructing biaryl systems.

Basic Information

Product Name	Ethyl 2-Chloro-3-Fluorobenzoate
CAS No.	1214379-08-4
Molecular Formula	C9H8ClFO2
Molecular Weight	202.61 g/mol
Synonyms	Ethyl 2-Chloro-3-fluorobenzoate; 2-Chloro-3-fluorobenzoic Acid Ethyl Ester; Benzoic acid, 2-chloro-3-fluoro-, ethyl ester; Ethyl o-chloro-m-fluorobenzoate; 3-Fluoro-2-chlorobenzoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Chloro-3-Fluorobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our commitment to consistent quality and traceability supports your development and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.