Description

2-Methoxy-3-Chloro-5-Fluoropyridine is a high-purity, multi-substituted pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique halogenated and methoxylated structure makes it an indispensable intermediate for creating complex molecules with targeted biological activity. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Building block for synthesizing functionalized polymers and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	2-Methoxy-3-Chloro-5-Fluoropyridine
CAS No.	1214377-00-0
Molecular Formula	C6H5ClFNO
Molecular Weight	161.56 g/mol
Synonyms	3-Chloro-5-fluoro-2-methoxypyridine; 5-Fluoro-3-chloro-2-methoxypyridine; 2-Methoxy-3-chloro-5-fluoropyridine; Pyridine, 3-chloro-5-fluoro-2-methoxy-; 1214377-00-0
EINECS	Contact for details

Quality Control

Our 2-Methoxy-3-Chloro-5-Fluoropyridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.