Description

Ethyl 2,5-Dibromopyridine-3-Carboxylate is a high-purity, multi-functional brominated pyridine derivative essential for advanced organic synthesis. This compound serves as a critical building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for its versatile reactivity as a halogenated synthon.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the pyridine core's bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl and heterobiaryl structures.
• Nucleophilic Substitution: The bromine atoms provide sites for further functionalization via substitution with various nucleophiles.

Basic Information

Product Name	Ethyl 2,5-Dibromopyridine-3-Carboxylate
CAS No.	1214375-74-2
Molecular Formula	C8H7Br2NO2
Molecular Weight	308.96 g/mol
Synonyms	Ethyl 2,5-dibromonicotinate; 3-Pyridinecarboxylic acid, 2,5-dibromo-, ethyl ester; 2,5-Dibromopyridine-3-carboxylic acid ethyl ester; Ethyl 2,5-dibromo-3-pyridinecarboxylate; 1214375-74-2; Ethyl 2,5-dibromonicotinate; 2,5-Dibromo-3-(ethoxycarbonyl)pyridine
EINECS	Contact for details

Quality Control

Our Ethyl 2,5-Dibromopyridine-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and internal quality standards. Our commitment to traceability and documentation supports regulatory requirements for advanced R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.