Description

3-Bromo-6-(Trifluoromethyl)Pyridine-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced chemical synthesis. Its core value lies in the strategic combination of a bromine substituent for cross-coupling reactions and a carboxylic acid group for derivatization, all on a trifluoromethylated pyridine scaffold prized for its ability to modulate the physicochemical properties of target molecules. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of novel organic electronic materials, such as those for organic light-emitting diodes (OLEDs) and semiconductors.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Chemical Biology Probes: Useful for constructing molecular probes and tags for studying biological processes and target engagement.

Basic Information

Product Name	3-Bromo-6-(Trifluoromethyl)Pyridine-2-Carboxylic Acid
CAS No.	1214373-82-6
Molecular Formula	C7H3BrF3NO2
Molecular Weight	269.99 g/mol
Synonyms	2-Pyridinecarboxylic acid, 3-bromo-6-(trifluoromethyl)-; 3-Bromo-6-(trifluoromethyl)picolinic acid; 3-Bromo-6-trifluoromethylpyridine-2-carboxylic acid; 3-Bromo-6-(trifluoromethyl)-2-pyridinecarboxylic acid; 1214373-82-6; 3-Bromo-6-trifluoromethyl-2-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-(Trifluoromethyl)Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.