Description

2-Chloro-3-Iodo-6-Methylpyridine is a halogenated pyridine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and valuable building block for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists for applications in cross-coupling reactions and as a precursor for functionalized heterocycles.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a precursor for synthesizing specialized ligands, catalysts, and organic electronic materials.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for Suzuki-Miyaura, Stille, and Negishi couplings, enabling precise carbon-carbon bond formation.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	2-Chloro-3-Iodo-6-Methylpyridine
CAS No.	1214372-51-6
Molecular Formula	C6H5ClIN
Molecular Weight	253.47 g/mol
Synonyms	3-Iodo-2-chloro-6-methylpyridine; 6-Methyl-2-chloro-3-iodopyridine; 2-Chloro-3-iodo-6-picoline; Pyridine, 2-chloro-3-iodo-6-methyl-; 2-Chloro-3-iodo-6-methylpyridine (IUPAC); 2-Cl-3-I-6-MePy
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-3-Iodo-6-Methylpyridine is manufactured under a strict quality management system. We provide comprehensive analytical documentation to ensure traceability and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. Our quality commitment aligns with cGMP principles for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.