Description

Methyl 6-Amino-3-(4-Fluorophenyl)Pyridine-2-Carboxylate is a high-value, fluorinated pyridine derivative that serves as a critical building block in modern synthetic chemistry. Its molecular structure, featuring both an amino group and a fluorinated aromatic ring, makes it an essential intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemists to explore new chemical spaces and structure-activity relationships (SAR).
• Ligand and Catalyst Development: The pyridine core and amino functionality make it suitable for creating specialized ligands in catalytic systems.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and advanced polymers.

Basic Information

Product Name	Methyl 6-Amino-3-(4-Fluorophenyl)Pyridine-2-Carboxylate
CAS No.	1214370-70-3
Molecular Formula	C13H11FN2O2
Molecular Weight	246.24 g/mol
Synonyms	6-Amino-3-(4-fluorophenyl)-2-pyridinecarboxylic acid methyl ester; Methyl 6-amino-3-(p-fluorophenyl)picolinate; 3-(4-Fluorophenyl)-6-aminopicolinic acid methyl ester; 2-Pyridinecarboxylic acid, 6-amino-3-(4-fluorophenyl)-, methyl ester; CAS 1214370-70-3
EINECS	Contact for details

Quality Control

Our production of Methyl 6-Amino-3-(4-Fluorophenyl)Pyridine-2-Carboxylate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent batch-to-batch quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.