Description

Ethyl 5-Chloro-2-Hydroxynicotinate is a high-purity organic intermediate of significant importance in advanced chemical synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides with improved efficacy.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials and photoactive compounds.
• Custom Synthesis & Contract Manufacturing: A vital substrate for custom synthesis houses producing specialized fine chemicals for client-specific projects.

Basic Information

Product Name	Ethyl 5-Chloro-2-Hydroxynicotinate
CAS No.	1214366-84-3
Molecular Formula	C8H8ClNO3
Molecular Weight	201.61 g/mol
Synonyms	5-Chloro-2-hydroxy-3-pyridinecarboxylic acid ethyl ester; Ethyl 5-chloro-2-oxo-1,2-dihydropyridine-3-carboxylate; 2-Hydroxy-5-chloronicotinic acid ethyl ester; 3-Carbethoxy-5-chloro-2-pyridone; 5-Chloro-2-pyridone-3-carboxylic acid ethyl ester; 1214366-84-3
EINECS	Contact for details

Quality Control

Our Ethyl 5-Chloro-2-Hydroxynicotinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting cGMP and ISO 9001 compliance for our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.