Description

Ethyl 2-Fluoro-3-Methylbenzoate is a high-purity fluorinated aromatic ester building block, essential for advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists working on new active ingredients, particularly in the life sciences sector.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel active pharmaceutical ingredients (APIs), especially those requiring fluorinated aromatic motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, and insecticides, where the fluorine atom can improve efficacy and environmental profile.
• Liquid Crystal & OLED Material Research: Used in the synthesis of fluorinated organic compounds for electronic applications, contributing to the development of new display and lighting technologies.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create biaryl structures.
• Ester Functional Group Manipulation: The ethyl ester group can be hydrolyzed to the corresponding acid, reduced to the alcohol, or used in further transesterification reactions.
• Fluorine Chemistry Library Building: A valuable component for constructing diverse compound libraries in medicinal chemistry for high-throughput screening and structure-activity relationship (SAR) studies.

Basic Information

Product Name	Ethyl 2-Fluoro-3-Methylbenzoate
CAS No.	1214363-24-2
Molecular Formula	C10H11FO2
Molecular Weight	182.19 g/mol
Synonyms	Ethyl 2-Fluoro-3-methylbenzoate; 2-Fluoro-3-methylbenzoic Acid Ethyl Ester; Benzoic acid, 2-fluoro-3-methyl-, ethyl ester; 3-Methyl-2-fluorobenzoic acid ethyl ester; Ethyl 3-methyl-2-fluorobenzoate; 2-Fluoro-m-toluic acid ethyl ester; Ethyl o-fluoro-m-toluate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Fluoro-3-Methylbenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.