Description

Ethyl 5-Bromo-2-Fluoro-3-Pyridinecarboxylate is a high-purity, multi-functional pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique halogenated structure, which enables precise molecular modifications and the introduction of key functional groups. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and antiviral compound libraries.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the bromo and fluoro substituents contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized heterocyclic compounds for organic electronic materials and liquid crystals.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects requiring specific halogenated pyridine scaffolds.

Basic Information

Product Name	Ethyl 5-Bromo-2-Fluoro-3-Pyridinecarboxylate
CAS No.	1214362-74-9
Molecular Formula	C8H7BrFNO2
Molecular Weight	248.05 g/mol
Synonyms	5-Bromo-2-fluoro-3-pyridinecarboxylic acid ethyl ester; Ethyl 5-bromo-2-fluoronicotinate; 3-Pyridinecarboxylic acid, 5-bromo-2-fluoro-, ethyl ester; 5-Bromo-2-fluoropyridine-3-carboxylic acid ethyl ester; 1214362-74-9
EINECS	Contact for details

Quality Control

Our Ethyl 5-Bromo-2-Fluoro-3-Pyridinecarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.